Dr. Neil H. Shusterman is Chief Medical Officer at Palladio Biosciences. Neil is board certified in internal medicine and nephrology and is a highly experienced drug developer. During his pharmaceutical industry career of over 31 years holding senior leadership positions in large, medium, and small companies, Neil contributed to the development or approval of numerous drugs across multiple therapeutic areas, including argatroban injection, Aveed®, Bystolic®, Combunox™, Coreg, Corlopam™, Savella®, Teveten®, Vraylar™, and Xiaflex®.
Prior to joining Palladio Biosciences, Neil worked at Endo Pharmaceuticals Inc., where he was the Chief Medical Officer with responsibility for 5 departments – Clinical Development and Operations, Medical Affairs, Drug Safety, Biometrics, and Scientific Communications; at Forest Laboratories, Inc., where he was Senior Vice President of Clinical Development at Forest Research Institute with responsibilities for Phase II to IV clinical development for five therapeutic areas – Cardiovascular, Pulmonary, Gastrointestinal/Metabolism, Psychiatry, and Neurology; and at SmithKline Beecham (subsequently GlaxoSmithKline), where he advanced to Vice President, Cardiovascular Therapeutic Area, North American Medical Affairs, Research and Development with worldwide responsibilities for all Phase II to IV cardiovascular drug development. During his tenure at SmithKline Beecham, Neil led the worldwide pivotal efficacy studies and regulatory filing for Coreg (carvedilol), the first beta-blocker approved for the treatment of chronic heart failure (CHF). That approval led to a paradigm-shift in the treatment of CHF, resulting in reduced morbidity and mortality in this devastating condition. In addition, Neil led several large cardiovascular morbidity and mortality studies that recruited 20,000 patients combined at hundreds of sites on 3 continents.
Before joining the pharmaceutical industry, Neil practiced nephrology at the University of Pennsylvania in Philadelphia, PA where he was Assistant Professor of Medicine and directed a large outpatient dialysis program. Neil has published and presented widely on topics in renal medicine, cardiovascular therapeutics, and drug development. He earned his undergraduate degree from the Pennsylvania State University and his M.D. from Sidney Kimmel Medical College of Thomas Jefferson University in Philadelphia, PA.